Investigation was carried out to study the effect of spacing and fertilizer on growth, yield and soil health in pigeonpea hybrid during 2007-08 and 2008-09. The results obtained showed significantly highest grain yield with row spacing of 90 cm (1371 kg/ha) followed by 75 cm (1329 kg/ha) over 60 cm (1193 kg/ha) and plant to plant spacing of 30 cm found superior over 20 cm, however, similar trend was obtained with net return. Application of different fertility levels recorded significantly higher grain yield and net return over control, however, difference between them remained at par, therefore, application of 20:45:20:20:15 kg NPKSZnSO4/ha was found economical. Soil fertility status after harvest of pigeonpea hybrid was significantly influenced due to spacing and fertility levels over initial status. Interaction effect due to different levels of fertilizer, FYM and biofertilizer were found to be non significant. The results show that sowing at 75 x 30 cm with application of 20:45:20:20:15 kg NPKSZnSO4/ha are essential for obtaining high grain yield as well as net return of pigeonpea hybrid.