A field experiment was conducted during rabi season of 2007-2008 to study the harmful effects of salinity and their amelioration by the use of plant growth regulators, viz. cycocel, maleic hyderazide, benzyle adenine and mixtalol on physiological, biochemical traits and yield attributes of wheat (Triticum aestivum L) cv. KRL-1-4. Salinity was found to significantly decrease photosynthetic rate, total chlorophyll content, cell membrane stability, reducing sugar content, plant height, leaf area index, test weight, number of grains/ear, number of tillers/ meter row length, grain and straw yield with a significant increase in nitrogen and protein content in grain compared to non saline field. Application of plant growth regulators ameliorated the effect of salinity on these parameters. Maximum increase in above parameters was recorded by the use of benzyl adenine at 75 mg.L-1 concentration as compared to other concentrations and other plant growth regulators.