Egg plant (Solanum melongena L.) is one of the most popular vegetable crop cultivated in India. Its yield is considerably reduced by many pests and diseases. Incorporation of resistant genes from wild relatives is the best alternative for increasing yield. Solanum indicum is a source of resistance for many pests and diseases. The present study was undertaken to produce inter-specific hybridization between S. melongena (Cultivated species) and S. indicum (Wild relative) in both ways. Developing embryos of 15 days old responded better for regeneration at MS Basal Medium + 5 ppm BAP + 3 ppm IAA and plantlets were produced with 20–25 days at the room temperature of 25±2°C and 75±5 per cent humidity. The photoperiod was maintained for 16 hrs with 2000 Lux in both direct and reciprocal hybrid embryos.