<div>The present study was conducted to evaluate the therapeutic efficacy of fipronil, ivermectin and clove oil against frequently reported Psoroptes cuniculi mites which are responsible for causing intense pruritus and scab formation on skin, ear pinna and ear canal in domestic rabbits (Oryctolagus cuniculus).&nbsp;The rabbits were divided into 3 groups viz. A, B and C each having 10 rabbits. These groups were topically treated with fipronil, ivermectin and clove oil on days 0, 7, 14 and 21. Pre and post treatment evaluations were made on the basis of clinical improvement and microscopic examination of skin scrapings in each group.&nbsp;Results revealed that all 3 drugs were effective against P. cuniculi; but ivermectin led recovery was quicker than rest of the two drugs. All three groups were free of lesions and mites on day 21 of treatment.&nbsp;</div>

<div>Comparative Efficacy of Fipronil, Ivermectin and Clove Oil (Eugenia caryophyllata) against Psoroptes cuniculi Mites in Rabbits (Oryctolagus cuniculus)</div>

Background: Mange is responsible huge economic losses due to reduced milk production, degradation of hide. 
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Methods: A total 302 buffalo were screened for mange for a period of six month (August 2023 to January 2024) in Rajasthan state in India and the animal were subjected through physical and clinical examination. Skin scrapping sample were collected for mange identification. Blood sample were also collected for haemato-biochemical parameter investigations. 
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Result: Overall prevalence of mange was found 5.62 per cent and the per cent distribution of sarcoptic mange was higher (58.82 per cent) as compared to psoroptic mange (41.17 per cent). Age group-wise prevalence of mange was recorded highest in buffalo below 6 months age, followed by 6 months to 3 years age group and lowest in buffalo above 3 years of age. Female animals were more affected with mange than the male animals.Clinical examination revealed pruritus was a common clinical sign of mange.&nbsp; There was highly significant (p&lt;0.01) difference in Hb, PCV, TEC, lymphocyte, eosinophils, total protein, albumin, globulin in mange affected buffalo as compared to healthy control.

Comparative Efficacy of Fipronil, Ivermectin and Clove Oil (Eugenia caryophyllata) against Psoroptes cuniculi Mites in Rabbits (Oryctolagus cuniculus)

Prevalence, Clinico-haemato-biochemical Studies on Mange in Buffalo