Background: Soil mediated/ transmitted helminthiasis (STH/SMH) is a neglected tropical disease and includes Ascarids, Trichuris and Hookworms, which prominently affects population living either in the low sanitary condition or in close proximity with the animals. Recent years have witnessed elevation in the Trichuris infection, with India ranking first globally. Variety of factors including low sanitation, close contact with animals, increased man and wild conflict contribute towards STH. However, co-relation of STH/SMH infection from wildlife have not been studied. 
 
Methods: The study was conducted for a period of 1 year from August, 2021 to September, 2022. Trichuris infection was present in 72 out of 131 carcasses of wild animals with prevalence rate of 35%. The prevalence percentage of Trichuris infection in different sub categories of wild animals was calculated. Seasonal prevalence rate was calculated with increased cases reported in summer season followed by monsoon. Additionally, fecal samples, worms and intestinal samples for further studies were collected.&nbsp; 
 
Result: Wild animals act as bridge for transmission of various zoonotic diseases. However, zoonotic potential of parasitic diseases are neglected in wild animals with no systematic literature. Based on our study we illustrate that wild animals hold considerate potential plausibly demonstrating an iceberg phenomenon. Wildlife is an essential component in the epidemiology of many, if not most, zoonoses, wildlife should be taken into account in the risk analysis framework.

Soil Mediated Helminthiasis: A Study on Neglected Tropical Disease in Wild Animals in Haryana

<div style="text-align:justify">Background: A study was conducted to evaluate the antioxidant and immunological profile of methanolic extract of Adhatoda vasica leaves (AVE) in naturally infected sheep with gastrointestinal nematodes and compared with commonly used anthelmintic albendazole in sheep.&nbsp; 
 
Methods: Fifty four sheep found positive for gastrointestinal nematodes were divided into 3 equal groups, GI (infected-untreated: control), GII (infected- AVE treated) and GIII (infected- albendazole treated). Blood samples were drawn on 5th and 14th day after treatment for analysis of oxidative stress markers such as TBARS, TAC, SOD and catalase and immunological parameters such as total immunoglobulin, IgG and IL-10. 
 
Result: Helminthiasis in sheep cause a considerable oxidative stress. The anthelmintic activity of Adhatoda vasica surpassed the conventional synthetic drug albendazole in sheep in terms of oxidative and immunological changes in blood.</div>

Soil Mediated Helminthiasis: A Study on Neglected Tropical Disease in Wild Animals in Haryana

Effect of Adhatoda vasica (Acanthaceae) on Antioxidant and Immunological Profile in Sheep