Effect of selenium supplementation on glutathione peroxidase (GPX), cholesterol, thyroxin (T4) and other blood biochemicals in local Aseel

DOI: 10.18805/ijar.10765    | Article Id: B-472 | Page : 1051-1056
Citation :- Effect of selenium supplementation on glutathione peroxidase (GPX), cholesterol, thyroxin (T4) and other blood biochemicals in local Aseel .Indian Journal Of Animal Research.2017.(51):1051-1056

Waseem Muhammad Zia,  Anjum Khalique, Saima Naveed, Jibran Hussain  and Imran Muhammad 

doctorwsi639@gmail.com
Address :

Institute of Biochemistry & Biotechnology, University of Veterinary and Animal Sciences, Lahore-54000, Pakistan.

Submitted Date : 3-03-2016
Accepted Date : 20-05-2016

Abstract

The aim of study was to determine the impact of different selenium sources on blood biochemical picture of Aseel. Three-weeks-old 240 Aseel chickens (120 and 120 ) from Lakha, Mushki, Peshaweri and Mianwali varieties were randomly distributed into four groups; 60 birds/variety (30 and 30). The birds of each group of either sex were further subdivided into A, B (experimental) and C (control) treatment groups with 10 birds each. Group A and B were fed the diet containing 0.3 mg/kg Se-enriched yeast  and sodium selenite, respectively, while group C was fed diet without selenium (control diet). Birds were maintained individually in cages from 4 to 21 weeks. In blood serum, glutathione peroxidase (GPx) levels increased (P£0.05) while, total cholesterol and thyroxin (T4) levels decreased (P£0.05) in Se-yeast supplemented group than sodium selenite supplemented or control group. The study concluded that Se-enriched yeast gave the superior performance to improve blood biochemical profile of Aseel. 

Keywords

Antioxidant status Cholesterol Globulin Native Aseel Selenium Serum Thyroxin.

References

  1. AOAC. (1995). Official Methods of Analysis (13th edn), Association of Official Analytical Chemists, Washington, DC.
  2. Ankur, K. and Baghel, R.P.S. (2011). Effect of different levels of dietary selenium on growth performance and nutrient utilization of broiler birds. Veterinary World, 4:173-175.
  3. Beckett, G.J. and Arthur, J.R. (2005). Selenium and endocrine system. Journal of Endocrinology, 184:455-465.
  4. Bhatti, M.A., Qureshi, M.S. and Ahmad, A. (1991). Comparative study on the performance of various genetic groups of Aseel and its crosses with exotic breeds of poultry under controlled and field conditions. Second annual report of Pakistan Agriculture Research Council, Islamabad.
  5. Blackburn, H.D. (2006). The national animal germplasm program: challenges and opportunities for poultry genetic resources. Journal of Poultry Sciences, 85:210-215.
  6. Bunglavan, S.J., Garg, A.K., Dass, R.S. and Shrivastava, S. (2014). Effect of supplementation of different levels of selenium as nanoparticles/sodium selenite on blood biochemical profile and humoral immunity in male Wistar rats. Veterinary World, 7:1075-1081.
  7. Cruz, V.C. and Fernandez, I.B. (2011). Effect of organic selenium and zinc on the performance and egg quality of Japanese quails. Brazilian Journal of Poultry Science, 13:91-95.
  8. Chun, F., Bing, Y. and Daiwen, C. (2009). Effects of different sources and levels of selenium on performance, thyroidfunction and antioxidant status in stressed broiler chickens. International Journal of Poultry Science, 8:583-587.
  9. Dalto, D.B., Roy, M., Audet, I., Palin, M.F., Guay, F., Lapointe, J. and Matte, J.J. (2015). Interaction between vitamin B6 and source of selenium on the response of the selenium-dependent glutathione peroxidase system to oxidative stress induced by estrus in pubertal pig. Journal of Trace Elements in Medicine and Biology, 32:21-29.
  10. Ekue, F.N., Pone, K.D., Mafeni, M.J., Nfi, A.N. and Njoya, J. (2002). Survey of the traditional poultry production system in the Bamenda area, Cameroon. In: Characteristics and parameters of family.
  11. Ferit, M.G., Sahin, N. and Kucuk, O. (2003). Effects of vitamin E and selenium on thyroid status, adrenocorticotropin hormone, and blood serum metabolite and mineral concentrations of Japanese quails reared under heat stress (34°C). Journal of Trace Element in Experimental Medicine, 16:95-104.
  12. Hatfield, D.L. and V.N. Gladyshev, (2002). How selenium has altered our understanding of the genetic code. Molecular and Cellular Biology, 22:3565-3576.
  13. Madkour, M., Ali, H.M., Yassein, S.A., Abdel-Fattah, S.A., Hewida, El-Allawy, M. and El-Wardany, I. (2015). Effect of dietary organic selenium supplement on growth and reproductive performance of Japanese quail breeders and their progeny and its relation to antioxidation and thyroid activity. International Journal of Poultry Science, 14:317-324.
  14. Mikulskil, D., Jankowski, J., Zdunczyk, Z., Wroblewska, M., Sartowska, K. and Majewska, T. (2009). The effect of selenium source on performance, carcass traits, oxidative status of the organism, and meat quality of turkeys. Journal of Animal Feed Sciences, 18:518-530.
  15. Mohapatra, P., Swain, R.K., Mishra, S.K., Behera, T., Swain, P., Mishra, S.S., Behura, N.C., Sabat, S.C., Sethy, K., Dhama, K. and Jayasankar, P. (2014). Effects of dietary nano selenium on tissue selenium deposition, antioxidant status and immune functions in layer chicks. International Journal of Pharmacology, 10: 160-167.
  16. NRC. (1994). Nutrient Requirements of Poultry (9th edn), National Academy Press; Washington, D.C.
  17. Okunlola, D.O., Akande, T.O. and Nuga, H.A. (2015). Hematological and serum characteristics of broiler birds fed diets supplemented with varying levels of selenium powder. Journal of Biology, Agriculture and Healthcare, 5:107-110.
  18. Ozbal, S., Erbil, G., Kocdor, H., Tugyan, K., Pekcetin, C. and Ozogul, C. (2008). The effects of selenium against cerebral ischemia-reperfusion injury in rats. Neuroscience Letter, 438:265-269.
  19. Peric, L., Milosevic, N., Zikic, D., Kanacki, Z., Dzinic, N., Nollet, L. and Spring, P. (2009). Effect of selenium sources on performance and meat characteristics of broiler chickens. Journal of Applied Poultry Research, 18:403-409.
  20. Ramezani, S., Riasi, A., Afzali, N. and Fathi Nasari, M.H. (2011). Effect of selenium and sodium bicarbonate supplementation diets on blood biochemical properties, growth performance and carcass traits of broilers in heat stress condition. Agricultural Scientific Information and Documentation Centre, Agricultural Research and Education Organization, Iran.
  21. Singh, M., Singh, U., Gupta, R.K. and Gurung, B.S. (2005). Poultry farmers and rearing systems in the breeding tract of Aseel fowl. Indian Journal of Animal Sciences, 70: 1183-1184.
  22. Srimongkol, C. (2003). Effects of selenium supplementation on growth performance, thyroid hormone (T3) levels, antioxidant enzyme and disaccharidase activities in broiler chicks. Thesis M.Sc. Chulalongkorn University.
  23. Upton, J.R, Edens, F.W., Ferket PR. (2008). Selenium yeast effect on broiler performance. International Journal of Poultry Science, 7:798-805.
     

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