Expression of Stearoyl Co-enzyme A desaturase (SCD) gene during the juvenile age in layer chicken

DOI: 10.18805/ijar.B-3698    | Article Id: B-3698 | Page : 1436-1439
Citation :- Expression of Stearoyl Co-enzyme A desaturase (SCD) gene during the juvenile age in layer chicken.Indian Journal Of Animal Research.2019.(53):1436-1439
N. Govardhana Sagar, T.K. Bhattacharya, A. Rajendra Prasad, Pushpendra Kumar, R.N.Chatterjee, Bharat Bhushan and K.K Kanaka bhattacharyatk@gmail.com
Address : Division of Animal Genetics, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly-243 122, Uttar Pradesh, India.
Submitted Date : 28-07-2018
Accepted Date : 19-12-2018

Abstract

Stearoyl-CoA desaturase (SCD) is key enzyme in the production of triglycerides and cholesterol. Present study was conducted to know the expression pattern of the Stearoyl-CoA desaturase (SCD) gene in liver during juvenile age (0 day, 14th day, 28th day and 42nd day) in layer birds. Expression of SCD gene increased from the day of hatch to 42nd day, as the body weight and fat deposition increased. The mRNA expression levels of SCD gene during day 0 was differed significantly (P<0.05) with expression levels during other juvenile ages. When compared with SCD expression levels on the day 0 expression levels were up-regulated by 8198.64, 7245.99 and 5587.77 folds over day 14,  28 and  42 respectively. Serum concentration of triglycerides and cholesterol were found to be proportional to the expression levels of SCD gene in liver. It is concluded that SCD expression varied among different age groups during juvenile stages and had significant association with serum triglycerides and cholesterol concentration in layer chicken.

Keywords

Cholesterol MRNA Stearoyl-CoA desaturase (SCD) Triglycerides.

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