Effect of mannan-oligosaccharides (MOS) supplementation on performance, immunity and HSP70 gene expression in broiler chicken during hot-dry summer 

DOI: 10.18805/ijar.B-3291    | Article Id: B-3291 | Page : 868-874
Citation :- Effect of mannan-oligosaccharides (MOS) supplementation onperformance, immunity and HSP70 gene expression in broilerchicken during hot-dry summer.Indian Journal Of Animal Research.2018.(52):868-874
J.J. Rokade, Mukesh Kagate, S.K. Bhanja, M. Mehra, A. Goel, Mayur Vispute and A.B. Mandal jaydeepvet@gmail.com
Address : ICAR-Central Avian Research Institute, Izatnagar-243 122, Uttar Pradesh, India
Submitted Date : 12-08-2016
Accepted Date : 1-06-2017

Abstract

An experiment was conducted on broiler chicks (n=120), reared in cages on a standard diet up to 14th day of age and thereafter up to 42nd day (14-42d) on test diets with or without MOS. The 14th day old chicks were randomly distributed into three dietary treatment groups viz., T1 (control diet), T2 (control diet with MOS @ 0.3%) and T3 (control diet with MOS @ 0.5%). Each dietary treatment comprised of four replicates of eight birds each. Experiment was carried out during hot-dry summer. It was found that production indices improved (P<0.001) significantly during all phases. Cellular and humoral immunity at 28th day of age improved significantly (P<0.05) due to MOS supplementation. The percentage of hemoglobin, protein, AST and ALT increased significantly (P<0.001) in MOS supplemented group at 28th as well as 42nd day of age. While H:L ratio, serum corticosterone and cholesterol levels decreased significantly (P<0.001) in MOS supplemented groups. Supplementation of MOS at the both levels caused significant (P<0.001) down regulation of HSP70 expression in jejunum tissues during 28th and 42nd day. Based on this study it was concluded that supplementation of 0.3% MOS in broiler diets significantly improved their performance and welfare during heat stressed conditions. 

Keywords

Broilers Corticosterone Heat stress HSP70 MOS Production performance.

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