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Current IssueEditorial BoardOnline First Articles
Indian Journal of
Animal Research
Print ISSN: 0367-6722
Online ISSN: 0976-0555
NASS Rating
6.40
SJR
0.233
CiteScore
0.606

Chief Editor:
M. R. Saseendranath
Kerala Veterinary and Animal Science University, Mannuthy, Thrissur, INDIA
Frequency:Monthly
Indexing:
Science Citation Index Expanded, BIOSIS Preview, ISI Citation Index, Biological Abstracts, Scopus, ...

Research Article

Indian Journal of Animal Research, volume 53 issue 9 (september 2019) : 1210-1216

Effect of glutamine on the intestinal function and health of broilers challenged with Salmonella pullorum

Q.J. Wu, C.Jiao, Z.H. Liu, S.W. Li, D.D. Zhu, W.F. Ma, Y.Q. Wang, Y. Wang, X.H. Wu
1College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, Henan, PR China.
Cite article:- Wu Q.J., C.Jiao, Liu Z.H., Li S.W., Zhu D.D., Ma W.F., Wang Y.Q., Wang Y., Wu X.H. (2019). Effect of glutamine on the intestinal function and health of broilers challenged with Salmonella pullorum. Indian Journal of Animal Research. 53(9): 1210-1216. doi: 10.18805/ijar.B-1133.

ABSTRACT

The influence of glutamine (Gln) on the intestinal function and health in broilers challenged with Salmonella pullorum was investigated. 240 one -day-old Arbor Acres broilers were divided into four groups in a completely randomized design, each of which included 6 replicates with 10 birds per replicate, for 21 days. The experimental groups were as follows: control group (CON), S. pullorum challenged control group (SCC), basal diet plus S. pullorum challenged plus 0.5 % Gln (Gln 1) or1.0 % Gln (Gln 2), The results showed that S. pullorum had significantly adverse effect on ADG, ADFI and feed to gain ratio (F: G) of broilers compared with the values measured for the CON during days 5 to 7. Moreover, compared with the characteristics of CON, S. pullorum showed significantly effects on the relative weight and length of small intestine at 7 d, the activities of sucrose, maltase and lactase in the jejunum mucosa at 4 d, or 7 d, the counts of Salmonella and Lactobacillus at 4, 7 and 21d and the molar proportion of isobutyric acid at 14 d. The inclusion of Gln significantly elevated the relative weight and length of small intestine, increased intestinal sucrose, maltase and lactase activities, decreased caecal Salmonella population and molar proportion of isobutyric acid at 14 d. These results suggested that Gln might exert a favorable effect on intestinal function and health in broilers. 

REFERENCES

  1. Bohez, L., Dewulf, J., Ducatelle, R., Pasmans, R., Haesebrouck, F., Van Immersee, F. (2008). The effect of oral administration of a homologous hilA mutant strain on the long-term colonization and transmission of Salmoella Enteritides in broiler chickens. Vaccine, 26: 372-378.
  2. Giancamillo, A.D., Domeneghini, C., Paratte, R., Dell’Orto, V., Bontempo, V. (2003). Oral feeding with L-Glutamine and Nucleotides: impact on some GALT (gut associated lymphoid tissue) parameters and cell proliferation/death rates in weaning piglets. Italian Journal of Animal Science, 2: sup1, 364-366.
  3. Horvath, K.J., Hill, M., Papadimitriou, I., Magder, J., Chanasongcram, L.S. (1996). Isocaloric glutamine-free diet and the morphology and function of rat small intestine. Journal of Parenteral and Enteral Nutrition, 20(2): 128-135.
  4. Jiang, Z.Y., Sun, L.H., Lin, Y.C., Ma, X.Y., Zheng, C.T., Zhou, G.L., Chen, F., Zou, S.T. (2009). Effects of dietary glycyl-glutamine on growth performance, small intestinal integrity and immune responses of weaning piglets challenged with lipopolysaccharide. Journal of Animal Science, 87:4050–4056.
  5. NRC. (1994) Nutrient Requirements of Poultry, 9th edn. Natl. Acad. Press, Washington.
  6. Sapre, V.A., Mehta, M.L. (1970). Haematological changes in Salmonella infections in poultry. Indian Journal of Animal Sciences, 456-463. 
  7. Shao, Y.X., Lei, Z., Yuan, J.M., Yang, Y., Guo, Y.M., Zhang B.K. (2014). Effect of zinc on growth performance, gut morphometry and cecal microbial community in broilers challenged with Salmonella enterica serovar Typhimurium. Journal of Microbiology, 52(12): 1002-1011.
  8. Singh, D.K., Singh, K.S., Paswan, V.K. (2018). Comparative production performance of Hubbard, Vencobb and Vencobb-400 broiler strains during tropical summer season. Indian Journal of Animal Research, DOI: 10.18805/ijar.B-3553.
  9. Rosa. C.V.D.da, Azevedo, S.C.S.F., Bazotte, R.B., Peralta, R.M., Buttow, N.C., Pedrosa, M.M.D., Vilma, A.F.de.G.,
  10. Maria, R.M.N. (2015). Supplementation with L-Glutamine and L-Alanyl-L-Glutamine changes biochemical parameters and jejunum morphophysiology in type 1 diabetic wistar rats. PLoS One, 10(12): e0143005.
  11. Uni, Z., Noy, Y., Sklan, D. (1999). Posthatch development of small intestinal function in the poultry. Poultry Science, 78: 215-222.
  12. Wang, L.C., Zhang, T.T., Wen, C., Jiang, Z.Y., Wang, T., Zhou, Y.M. (2012). Protective effects of zinc-bearing clinoptilolite on broilers challenged with Salmonella pullorum. Poultry Science, 91(8): 1838-1845.
  13. Wu, G. (2013). Functional amino acids in nutrition and health. Amino Acids, 45:407-411.
  14. Wu, Q.J., Zheng, X.C., Wang, T., Zhang, T. Y. (2018). Effect of dietary oridonin supplementation on growth performance, gut health and immune response of broilers infected with Salmonella pullorum. Irish Veterinary Journal, 71:16-21.
  15. Wu, Q.J., Liu, N., Wu, X.H., Wang, G.Y., Lin, L. (2018). Glutamine alleviates heat stress-induced impairment of intestinal morphology, intestinal inflammatory response and barrier integrity in broilers. Poultry Science, 97(8): 2675-2683.
  16. Xu, C.L., Sun, R., Qiao, X.J., Xu, C.C., Shang, X.Y., Niu, W.N. (2014). Protective effect of glutamine on intestinal injury and bacterial community in rats exposed to hypobaric hypoxia environment. World journal of gastroenterology, 20(16): 4662-4674.
  17. Xue, G. D., Barekatain, R., Wu, S. B., Choct, M., Swick, R. A. (2018). Dietary L-glutamine supplementation improves growth performance, gut morphology and serum biochemical indices of broiler chickens during necrotic enteritis challenge. Poultry Science, 97(4):1334-1341. 
  18. Zhou, G., Wang, J. G., Zhu, X. Q., Wu, Y. F., Gao, M.M., Shen, H. (2014). Induction of maggot antimicrobial peptides and treatment effect in Salmonella pullorum-infected chickens. Journal of Applied Poultry Research, 23(3): 376-383.
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