Dose dependent effects of Spirulina Platensis on liver health in rats

DOI: 10.18805/ijar.B-1055    | Article Id: B-1055 | Page : 349-353
Citation :- Dose dependent effects of Spirulina Platensis on liver health in rats.Indian Journal Of Animal Research.2020.(54):349-353
Nilay Seyidoglu, Sevda Inan and Nazmiye Gunes nseyidoglu@nku.edu.tr
Address :
Tekirdag Namik Kemal University, Faculty of Veterinary, Department of Physiology, Degirmenalti Campus, Suleymanpasa, Tekirdag, Turkey.
Submitted Date : 15-10-2018
Accepted Date : 16-04-2019

Abstract

Spirulina platensis which is an important microalgae is interested in both human and animal nutrition for health balance. This study’s aimed to evaluate the dose dependent effects of S.platensis on body weight, height, waist circumference (WC), body mass index (BMI), waist/height ratio (WHtR), abdominal fat weight, liver weight, serum liver enzymes and liver histopathology. 30 male Wistar albino rats’re used in groups; Control, SP-1(500mg/kgbw) and SP-2(1000mg/kgbw). S.platensis was administered by oral gavage daily. The body weight, height, WC, BMI, WHtR and abdominal lipid weight were calculated. Also, serum cholesterol, ALT and AST were measured. End of the study, liver tissue samples were taken and scaled and histopathologic changes were recorded. There were no differences in body conditions, but positively significant correlations were found among parameters. As the doses were considered, in groupSP-1, significant positively correlations were determined among abdominal fat, growth, height, BMI and WC statistically. Nevertheless, there were no significant changes in liver weight, serum and histopathologic analyzes. S.platensis with its high concentration of functional nutrients is called as an important alternative therapeutic food and it can be used safely.

Keywords

Body condition Cholesterol Liver health Microalgae Spirulina platensis.

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