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Current IssueEditorial BoardOnline First ArticlesArchive

volume 41 issue 3 (september 2007) : 223 - 225

CHANGES IN THE BLOOD LIPID PROFILE AFTER ADMINISTRATION OF MURRAYA KOENIGII SPRENG (CURRY LEAF) EXTRACTS IN THE NORMAL SPRAGUE DAWLEY RATS

M
M.K. Vinuthan*
V
V. Girish Kumar*
J
J.P. Ravindra**
P
P.S.P. Gupta**
S
S.J. Arun***
1Central Animal House, University of Agricultural Sciences, Bangalore - 560 024, India

  • Submitted|

  • First Online |

  • doi

Cite article:- Vinuthan* M.K., Kumar* Girish V., Ravindra** J.P., Gupta** P.S.P., Arun*** S.J. (2025). CHANGES IN THE BLOOD LIPID PROFILE AFTER ADMINISTRATION OF MURRAYA KOENIGII SPRENG (CURRY LEAF) EXTRACTS IN THE NORMAL SPRAGUE DAWLEY RATS. Indian Journal of Animal Research. 41(3): 223 - 225. doi: .

ABSTRACT

Aqueous and methanol leaf extract of Murraya koenigii were investigated for hypolipidemic
effects on male Sprague Dawley rats. The rats were divided into three groups of six animals each.
The first group (I) received vehicle alone to serve as control. The second (II) and third (III) groups
received aqueous extract (600 mg/kg b.w.) and methanol extract (200 mg/kg b.w.) respectively
daily orally for a period of eight weeks. There were no significant changes in lipid profile in group
I rats. In groups II and III plasma cholesterol, triglycerides and phospholipids levels were significantly decreased when compared to group I. The decrease in the lipid profile may be due to the constituents present in the leaf which are found to stimulate insulin secretion. The present study therefore suggests that these extracts exert hypolipidemic activities in treated rats

KEYWORDS

    REFERENCES

    1. Ackermann, P.G. and Toro, G. (1963). In: Gradwohl’s Clinical Laboratory Methods and Diagnosis. (Frankel, S. and
    2. Reitman, S. eds.) St. Louis, Sonnenwith, pp. 249-258.
    3. Allain, C.C. et al. (1974). Clin. Chem., 20: 470-475.
    4. Berne, R.M. and Levy, M.N. (1988). Physiology. 2nd Edn. The C. V. Mosby Company, Westline Industrial Drive, St.
    5. Louis, Missouri.
    6. Bhat, S.S. (1995). M.V.Sc. Dissertation, University of Agricultural Science, Bangalore, India.
    7. Chopra, R.N. et al. (1956). Glossary of Indian Medicinal Plants. CSIR, New Delhi.
    8. Drury, H.C. (1978). The Useful Plants of India. Allen, London.
    9. Footsati, S. and Prencipe, L. (1982). Clin. Chem., 28: 2077-2080.
    10. Khan, B.A. et al. (1995). Indian J. Biochem. Biophys., 32: 106-108.
    11. Khan, B.A. et al. (1997). Indian J. Exp. Biol., 35: 148-150.
    12. Khan, B.A. et al (1998). J. Food Sci. Technol., 35: 66-68.
    13. Kumar, V.S. et al. (1999). JMAPS., 21: 1139-1144.
    14. Levinson, S.A. (1969). Clinical Laboratory Diagnosis, 467-469.
    15. Pruthi, J.S. (1979). Spices and Condiment. National Book Trust, Green Park, J.K. Offset Printers, New Delhi.
    16. Rupashree, A.R. (1999). M.V.Sc. Dissertation, University of Agricultural Science, Bangalore, India.
    17. Santhakumari, G. et al. (1987). Bull. Med. Ethno. Bot. Res., 6: 189-195.
    18. Satyanarayana, U. (1999). Metabolism in Biochemistry. (Sen, Arunabha, ed.) Books and Allied (P) Ltd., Calcutta.
    19. Snedecor, G.W and Cochran, W.G. (1976). Statistical Methods. 6th Edn. Oxford and IBH Publishing Co., Calcutta.
    20. Zammit, V.A. (1996). Biochem. J., 314: 1-14.
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      volume 41 issue 3 (september 2007) : 223 - 225

      CHANGES IN THE BLOOD LIPID PROFILE AFTER ADMINISTRATION OF MURRAYA KOENIGII SPRENG (CURRY LEAF) EXTRACTS IN THE NORMAL SPRAGUE DAWLEY RATS

      M
      M.K. Vinuthan*
      V
      V. Girish Kumar*
      J
      J.P. Ravindra**
      P
      P.S.P. Gupta**
      S
      S.J. Arun***
      1Central Animal House, University of Agricultural Sciences, Bangalore - 560 024, India

      • Submitted|

      • First Online |

      • doi

      Cite article:- Vinuthan* M.K., Kumar* Girish V., Ravindra** J.P., Gupta** P.S.P., Arun*** S.J. (2025). CHANGES IN THE BLOOD LIPID PROFILE AFTER ADMINISTRATION OF MURRAYA KOENIGII SPRENG (CURRY LEAF) EXTRACTS IN THE NORMAL SPRAGUE DAWLEY RATS. Indian Journal of Animal Research. 41(3): 223 - 225. doi: .

      ABSTRACT

      Aqueous and methanol leaf extract of Murraya koenigii were investigated for hypolipidemic
      effects on male Sprague Dawley rats. The rats were divided into three groups of six animals each.
      The first group (I) received vehicle alone to serve as control. The second (II) and third (III) groups
      received aqueous extract (600 mg/kg b.w.) and methanol extract (200 mg/kg b.w.) respectively
      daily orally for a period of eight weeks. There were no significant changes in lipid profile in group
      I rats. In groups II and III plasma cholesterol, triglycerides and phospholipids levels were significantly decreased when compared to group I. The decrease in the lipid profile may be due to the constituents present in the leaf which are found to stimulate insulin secretion. The present study therefore suggests that these extracts exert hypolipidemic activities in treated rats

      KEYWORDS

        REFERENCES

        1. Ackermann, P.G. and Toro, G. (1963). In: Gradwohl’s Clinical Laboratory Methods and Diagnosis. (Frankel, S. and
        2. Reitman, S. eds.) St. Louis, Sonnenwith, pp. 249-258.
        3. Allain, C.C. et al. (1974). Clin. Chem., 20: 470-475.
        4. Berne, R.M. and Levy, M.N. (1988). Physiology. 2nd Edn. The C. V. Mosby Company, Westline Industrial Drive, St.
        5. Louis, Missouri.
        6. Bhat, S.S. (1995). M.V.Sc. Dissertation, University of Agricultural Science, Bangalore, India.
        7. Chopra, R.N. et al. (1956). Glossary of Indian Medicinal Plants. CSIR, New Delhi.
        8. Drury, H.C. (1978). The Useful Plants of India. Allen, London.
        9. Footsati, S. and Prencipe, L. (1982). Clin. Chem., 28: 2077-2080.
        10. Khan, B.A. et al. (1995). Indian J. Biochem. Biophys., 32: 106-108.
        11. Khan, B.A. et al. (1997). Indian J. Exp. Biol., 35: 148-150.
        12. Khan, B.A. et al (1998). J. Food Sci. Technol., 35: 66-68.
        13. Kumar, V.S. et al. (1999). JMAPS., 21: 1139-1144.
        14. Levinson, S.A. (1969). Clinical Laboratory Diagnosis, 467-469.
        15. Pruthi, J.S. (1979). Spices and Condiment. National Book Trust, Green Park, J.K. Offset Printers, New Delhi.
        16. Rupashree, A.R. (1999). M.V.Sc. Dissertation, University of Agricultural Science, Bangalore, India.
        17. Santhakumari, G. et al. (1987). Bull. Med. Ethno. Bot. Res., 6: 189-195.
        18. Satyanarayana, U. (1999). Metabolism in Biochemistry. (Sen, Arunabha, ed.) Books and Allied (P) Ltd., Calcutta.
        19. Snedecor, G.W and Cochran, W.G. (1976). Statistical Methods. 6th Edn. Oxford and IBH Publishing Co., Calcutta.
        20. Zammit, V.A. (1996). Biochem. J., 314: 1-14.
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          Follow us
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          Indian Journal of Animal Research

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