Bhartiya Krishi Anusandhan Patrika, volume 36 issue 3 (september 2021) : 173-177

​Importance of Genetic Polymorphism of Goat Milk Proteins on Human Nutrition and Health: A Review

A.S. Meena, Rajiv Kumar, S.S. Misra, Arun Kumar, Samlesh Kumari, D. Malakar, S. De
1ICAR- Central Sheep and Wool Research Institute, Avikangar-304 501, Rajasthan, India.
  • Submitted05-08-2021|

  • Accepted08-09-2021|

  • First Online 17-09-2021|

  • doi 10.18805/BKAP347

Cite article:- Meena A.S., Kumar Rajiv, Misra S.S., Kumar Arun, Kumari Samlesh, Malakar D., De S. (2021). ​Importance of Genetic Polymorphism of Goat Milk Proteins on Human Nutrition and Health: A Review. Bhartiya Krishi Anusandhan Patrika. 36(3): 173-177. doi: 10.18805/BKAP347.
The objective of the study is impotance of casein protein genetic polymorphism of goat milk. Goat milk is highly digestible and has medicinal properties in human being. Goat milk and its value added dairy products have higher demand in many contries of world. Due to evolution process, much genetic variability has been developed in casein protein genes. This is originatd due to point mutation; addition/deletion and many other factors lead to huge genetic variation in goat casein genes. Because of this goat milk, chemical and biological properties have been affected. Goat milk casein contents decide the cheese making properties as well as nutritional and medicinal values. Goat milk is good alternative source of nutrition in human when people have cow milk problems. Goat milk has humerous inactive bioactive peptides in their casein protein. These have important place for human health and nutrition. In the future, this is great possibility for development of medicinal value functional dairy products from functional bioactive peptides. 

  1. Caboni, P., Murgia, A., Porcu, A., Demuru, M., Giuseppe,  P., Nudda, A. (2016). Gas chromatography- mass spectrometry metabolomics of goat milk with different polymorphism at the alpha S1 casein genotype locus. J. Dairy Sci. 99: 1-6.

  2. Caroli, A., Chessa, S., Erhardt, G. (2009). Milk protein polymorphism in cattle: Effect on animal breeding and human nutrition. J. Dairy Sci. 92: 5335- 5352.

  3. Cosenza, G., Lannaccone, M., Pico, B.A., Ramunno, L., Capparelli, R. (2012). The SNP g1311T>C associated with the absence of beta casein in goat milk incluences CSN2 promoter activity. Animal Genetics, doi10.1111/age.12443.

  4. Gautam, D., Vats, A., Verma, M., Rout, P.K., Meena, A.S., Ali, M., Deepika, S., De, S. (2019). Genetic variation in CSN3 exon-4 region of Indian goats and a new nomenclature of CSN3 variants. Animal Genetics. 50: 191-192. 

  5. Gerlando, R., Tortorici, L., Sardina, M.T., Monteleone, G., Mastrangelo, S., Portolano, B. (2015). Molecular characterization of kappa casein gene in Girgentana dairy goat breed and identification of two new alleles. Italian Journal of Animal Science. 14: 90-93.

  6. Marletta, D., Criscione, A., Bordonaro, S., Guastella, A.M. and D’Urso, G. (2007). Casein polymorphism in goat’s milk. Lait. 86: 491-504. 

  7. Meena, A.S. (2020). Molecular characterization of casein gene(s) in Sirohi goat (Unpublished Ph. D thesis). ICAR-National Dairy Research Institute, Karnal- 132001 (Haryana), India. 

  8. Selvaggi, M., Laudadio, V., Dario, C., Tufarelli, V. (2014). Major proteins in goat milk: An updated overview on genetic variability. Mol. Biol. Rep. 41: 1035- 1048. 

Editorial Board

View all (0)