Prolonged ovarian acyclicity after parturition is one of the major problems faced by Bovine (Cattle and Buffalo) owners under field conditions. The present study was conducted on pre-selected 18 healthy and high milk producing crossbred cattle and Murrah graded buffaloes of Meerut region that did not show heat signs for 60-120 days’ post-partum. The ultrasonographic studies and gynaecological examination of genitalia further revealed absence of any perceptible follicular or luteal structures (smooth ovaries). The animals were initially dewormed using Fenbendazole (5 mg/Kg Body weight) followed by oral supplementation of chelated mineral mixture (50 g/day/animal for 30 days). Furthermore, they received injection of Tonophosphan (Intervet, @ 10 mL I/M /animal/week) for four weeks.  Finally, after completing the above treatment, all were given an injection of GnRH (@ 5 mL I/M, Receptal®VET) and the treated animals were monitored for oestrus detection. The oestrus was induced in 13 out of 18 bovines (72.22 %). Overall, the study revealed that the combined effect of dewormer, mineral supplementation, Tonophosphan and GnRH injection could be used successfully to induce heat and resume cyclicity in high yielding postpartum acyclic bovines. It also reflected the necessity for the need of improvement in the plane of nutrition in high yielding animals.