Agricultural Reviews

  • Chief EditorPradeep K. Sharma

  • Print ISSN 0253-1496

  • Online ISSN 0976-0741

  • NAAS Rating 4.84

Frequency :
Quarterly (March, June, September & December)
Indexing Services :
AGRICOLA, Google Scholar, CrossRef, CAB Abstracting Journals, Chemical Abstracts, Indian Science Abstracts, EBSCO Indexing Services, Index Copernicus
Agricultural Reviews, volume 42 issue 4 (december 2021) : 420-426

Potential Herbs as Eco-green Drugs for Aquaculture: A Review

S. Bharathi, Cheryl Antony, A. Uma, C. Sudhan, J. Praveenraj, Phibi Philip Naduvathu
1Dr. M.G.R Fisheries College and Research Institute, Ponneri-601 204, Tamil Nadu, India. 
Cite article:- Bharathi S., Antony Cheryl, Uma A., Sudhan C., Praveenraj J., Naduvathu Philip Phibi (2021). Potential Herbs as Eco-green Drugs for Aquaculture: A Review. Agricultural Reviews. 42(4): 420-426. doi: 10.18805/ag.R-2060.
Floral resources are abundant across the globe as it forms a key role in an ecological pyramid and enriched with a bunch of medicinal properties. Historical statue reveals various plants and its materials were used for treatments of different ailments and injuries and also used as nutraceuticals in humans and animals and also used for pest control in agriculture. The practice of using plants in aquaculture started in early 1990’s for various purposes by traditional farmers. Of late, due to overuse of fertilizers, antibiotics and other chemicals in aquaculture that created the environmental issues. As an alternative to chemicals and drugs, herbal based products can be used for eco and green aquaculture for safe and healthy fish productions. There are many potential herbal plants that have been identified and used in aquaculture and we focused on a few highly important herbal plants used in aquaculture. The potential herbal plants such as Aloe vera, Phyllanthus niruri, Azardirachta indica, Curcuma longa, Allium sativum, Ocimum sanctum, Zingiber officinale, Eclipta alba, Cissus quadrangularis, Acalypha indica could be used in fish farming. These herbal plants have versatile medicinal and therapeutic properties in fish, antioxidant, antifungal, antibacterial, antioxidant and immuno-stimulant. This review article gives information about the application of herbal plants in Aquaculture as a sustainable solution for safe and healthy fish productions.
  1. Abbasi Ghadikolaei., H, Kamali., A, Soltani, M. and Sharifian, M. (2017). Effects of Zingiber officinale powder on growth parameters, survival rate and biochemical composition of body in juvenile common carp (Cyprinus carpio). Iranian Journal of Fisheries Sciences.16: 67-85.
  2. Ahilan, B. and Jeyaseelan, MJP. (2010). Influence of certain herbal additives on the growth survival and disease resistance of goldfish, Carasstus auratas (Linnaeus), Tamil Nadu J. Veterinary and Animal Sciences. 6 (1): 5-11.
  3. Alam, M.N., Ahmed, G.U. and Chowdhury, M.B.R. (2014). Performance of herbal extracts on diseased fish. Bangladesh Journal of Veterinary Medicine. 12: 225-230.
  4. Alambra, J.R., Alenton, R.R.R., Gulpeo, P.C.R., et al. (2012). Immunomodulatory effects of turmeric, Curcuma longa (Magnoliophyta, Zingiberaceae) on Macrobrachium rosenbergii (Crustacea, Palaemonidae) against Vibrio alginolyticus (Proteobacteria, Vibrionaceae). Aquaculture, Aquarium, Conservation and Legislation. 5:13–17.
  5. Albert, V. and Ransangan, J. (2013). Antibacterial potential of plant crude extracts against Gram negative fish bacterial pathogens. International Journal of Research in Pharmaceutical and Biosciences. 3: 21–27.
  6. Al-Faragi, J.K. and Hassan, M.A.H. (2017). Efficiency of dietary turmeric on growth performance, hematology and survival rate in common carp Cyprinus carpio challenged with Flexibacter columnaris. Kufa Journal for Veterinary Medical Science.s8: 130–140.
  7. Alishahi, M., Ranjbar, M.M., Ghorbanpour, M., Peyghan, R., Mesbah, M. and Razi, J.M. (2010). Effects of dietary Aloe vera on some specific and nonspecific immunity in the common carp (Cyprinus carpio). International Journal of Veterinary Research. 4(3): 189-195.
  8. Aly, S.M., Atti, N.A., Mohamed, M.F. (2008). Effect of garlic on the survival, growth, resistance and quality of Oreochromis niloticus. In: From the pharaohs to the future. Eighth International Symposium on Tilapia in Aquaculture. Proceedings. Cairo, Egypt, 12-14 October, 2008. Aquafish Collaborative Research Support Program, pp 277-296.
  9. Aruldoss, K., Kannan, R., Divya, S. (2014). Effect of Cissus quadrangularis on the biochemical parameter in the fresh water fish, Oreochromis mossambicus. International Journal of Modern Research and Reviews. 2: 178-182.
  10. Bagalkotkar, G., Sagineedu, S.R., Saad, M.S. and Stanslas, J. (2006). Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review. Journal of Pharmacy and Pharmacology. 58: 1559-1570.
  11. Banerjee, S., Kim, L.M., Shariff, M., et al. (2013). Antibacterial activity of neem (Azadirachta indica) leaves on Vibrio spp. isolated from cultured shrimp. Asian J. Anim. Vet. Adv. 8: 355-361.
  12. Bhavan, P.S., Jeyanthi, S. and Rebecca, A.A. (2011). Growth performance of the freshwater prawn Macrobrachium rosenbergii post larvae fed with Ocimum sanctum (tulsi) and Withania somnifera (ashwagandha) incorporated feeds. International Journal of Biological Research and Development. 1: 34-53.
  13. Bhuvaneswari, R. and Balasundaram, C. (2006). Traditional Indian herbal extracts used in vitro against growth of the pathogenic bacteria-Aeromonashydrophila. The Israeli Journal of Aquaculture-Bamidgeh. 58(2): 89-96.
  14. Biswas, K., Chattopadhyay, I., Banerjee, R.K. and Bandyopadhyay, U. (2002). Biological activities and medicinal properties of neem (Azadirachta indica). Current Science 82: 10.
  15. Christybapita, D., Divyagnaneswari, M. and Michael, R.D. (2007). Oral administration of Eclipta alba leaf aqueous extract enhances the non-specific immune responses and disease resistance of Oreochromis mossambicus. Fish and Shellfish Immunology. 23: 840–852.
  16. Citarasu, T. (2010). Herbal biomedicines: a new opportunity for aquaculture industry. Aquaculture International. 18: 403-414.
  17. Das, B.K., Mukherjee, S.C., Sahu, B.B. and Murjani G. (1999). Neem (Azadirachta indica) extract as an antibacterial agent against fish pathogenic bacteria. Indian Journal of Experimental Biology. 37: 1097-1100.
  18. Das, R., Raman, RP., Saha, H. and Singh, R. (2015). Effect of Ocimum sanctum Linn.(Tulsi) extract on the immunity and survival of Labeo rohita (Hamilton) infected with Aeromonas hydrophila. Aquaculture Research. 46: 1111-1121.
  19. Devi, PU. (2001). Radioprotective, anticarcinogenic and antioxidant properties of the Indian holy basil, Ocimum sanctum (Tulasi). 
  20. Dügenci S.K., Arda, N., Candan, A. (2003). Some medicinal plants as immunostimulant for fish. Journal of Ethnopharmacology. 88: 99-106. https://doi.org/10.1016/S0378-8741(03)00182-X
  21. Gabriel, N.N., Qiang, J., Ma X.Y., et al. (2017). Sex-reversal effect of dietary Aloe vera (Liliaceae) on genetically improved farmed Nile tilapia fry. North American Journal of Aquaculture. 79: 100-105.
  22. Haghighi, M. and Rohani, M.S. (2013). The effects of powdered ginger (Zingiber officinale) on the haematological and immunological parameters of rainbow trout Oncorhynchus mykiss. Journal of medicinal Plant and Herbal Therapy Research. 1: 8-12.
  23. Haniffa, M.A., Bharathi, B.K., Margaret, I.V. and Paray, B.A. (2013). Effect of a Probiotic and Herbal Additives on Growth, Survival and Disease Resistance of Striped Murrel. World Aquaculture june: 64-67.
  24. Haniffa, M.A. and Margaret, I.V. (2014). Effect of Dietary Administration of the Herbal Additive Phyllanthus niruri on Growth Performance and Hematological Changes in Striped Snakehead. World Aquaculture. 66-68.
  25. Hassanin, M.E., Hakim, Y. and Badawi, M.E. (2014). Dietary effect of ginger (Zingiber officinale roscoe) on growth performance, immune response of nile tilapia (Oreochromis niloticus) and disease resistance against Aeromonas hydrophila. Abbassa Int. J. Aqua.7: 35–52.
  26. Hemapriya, V.S., Logambal, S.M. and Michael, R.D. (1997). Immunostimulation by leaf extracts of a few south Indian medicinal plants in Oreochromis mossambicus (Peters). Developmental and Comparative Immunology. 2: 175.
  27. Ibrahim, M., Khan, M., Rinard, J. and Mustafa, A. (2015). Determination of effective dosage of Phyllanthus niruri to modulate stress in tilapia, Oreochromis niloticus. Bioeng Biosci. 3: 68-71.
  28. Jagatheeswari, D., Deepa ,J., Ali, HSJ. and Ranganathan, P. (2013). Acalypha indica L.- An important medicinal plant: A review of its traditional uses and pharmacological properties. International Journal of Research in Botany. 3: 19-22.
  29. Joseph, B. and Raj, S.J. (2010). Pharmacognostic and phytochemical properties of Aloe vera linn an overview. International Journal of Pharmaceutical Sciences Review and Research. 4: 106-110.
  30. Kaur, R. and Shah, T.K. (2017). A review on role of plant waste products on fish growth, health and production. Journal of Entomology and Zoology Studies. 5: 583-589.
  31. Kim, K.H., Hwang, Y.J. and Bai, S.C. (1999). Resistance to Vibrio alginolyticus in juvenile rockfish (Sebastes schlegeli) fed diets containing different doses of aloe. Aquaculture. 180(1-2): 13-21.
  32. Krishnani, K.K., Gupta, B.P., Joseph, K.O. et al. (2002). Studies on the use of neem products for removal of ammonia from brackishwater. Journal of Environmental Science and Health, Part A. 37: 893-904.
  33. Kumar, B., Vijayakumar, M., Govindarajan, R. and Pushpangadan P. (2007). Ethnopharmacological approaches to wound healing-Exploring medicinal plants of India. Journal of Ethnopharmacology. 114: 103-113. https://doi.org/10.1016/j.jep.2007.08.010.
  34. Kumar, G., Karthik, L. and Rao, K.V.B. (2011). A Review on Pharmacological and Phytochemical Properties of Zingiber officinale Roscoe (Zingiberaceae). Journal of Pharmacy Research. 4(9): 2963-2966.
  35. Kyung, KH. (2012). Antimicrobial properties of Allium species. Curr Opin Biotechnol. 23: 142-147. https://doi.org/10.1016/j.copbio.2011.08.004.
  36. Labban, L. (2014). Medicinal and pharmacological properties of Turmeric (Curcuma longa): A review. Int. J. Pharm. Biomed Sci. 5(1): 17-23.
  37. Levy, G., Zilberg, D., Paladini, G and Fridman, S. (2015). Efficacy of ginger-based treatments against infection with Gyrodactylus turnbulli in the guppy [Poecilia reticulata (Peters)]. Veterinary parasitology. 209: 235-241.
  38. Logambal, S.M. and Michael, R.D. (2000). Immunostimulatory effect of azadirachtin in Oreochromismossambicus (Peters). Indian Journal of Experimental Biology. 38: 1092-1096.
  39. Mahmoud, M.M., El-Lamie, M.M., Dessouki, A.A. and Yusuf, M.S. (2014). Effect of turmeric (Curcuma longa) supplementation on growth performance, feed utilization and resistance of Nile tilapia (Oreochromis niloticus) to Pseudomonas fluorescens challenge. Global Research Journal of Fishery Science and Aquaculture. 1: 026-033.
  40. Malar, H.V. and Charles, P.M. (2013). Effect of Turmeric Curcuma longa Linn. Extract on immunity and resistance to Vibrio harveyi in black tiger shrimp Penaeus monodon. International Journal of Research in Zoology. 3: 21-26.
  41. Manoppo H., Kolopita M.E., Malatunduh R. (2016). Growth promoter effect of garlic (Allium sativum) on carp (Cyprinus carpio L). International Journal of Pharm. Tech. Research. 9: 283-288.
  42. Martins, ML., Moraes, FR., Miyazaki, DMY., et al. (2002). Alternative treatment for Anacanthorus penilabiatus (Monogenea: Dactylogyridae) infection in cultivated pacu, Piaractus mesopotamicus (Osteichthyes: Characidae) in Brazil and its haematological effects. Parasite. 9: 175-180.https://doi.org/10.1051/parasite/2002092175.
  43. Mishra, G., Srivastava, S. and Nagori, B.P. (2010). Pharmacological and therapeutic activity of Cissus quadrangularis: an overview. International Journal of Pharmtech. Research. 2: 1298-1310.
  44. Mithun, N.M., Shashidhara, S. and Vivek Kumar, R. (2011). Eclipta alba (L.) A review on its phytochemical and pharmacological profile. Pharmacology Online. 1: 345-357.
  45. Mohan, L., Amberkar, M.V. and Kumari, M. (2011). Ocimum sanctum Linn (Tulsi)-an overview. Int. J. Pharm. Sci. Rev. Res. 7: 51-53.
  46. Ranjbar, M., Ghorbanpoor, M., Peyghan, R., Mesbah, M. and Razi Jalali, M. (2010). Effects of dietary Aloe vera on some specific and nonspecific immunity in the common carp (Cyprinus carpio). Iranian Journal of Veterinary Medicine. 4(3): 295356. 10.22059/IJVM.2010.21352
  47. Mousa, M.A., El-Ashram, A.M. and Hamed, M.O.N.A. (2008). Effect of neem leaf extract on freshwater fishes and zooplankton community. In 8th International Symposium on Tilapia in Aquaculture. pp 307-318.
  48. Mukherjee, S.C. (1996). Training programme on fish diseases, their diagnosis and control. Central Institute of Freshwater Aquaculture (ICAR), Bhubaneswar, India.
  49. Muthulakshmi, M., Subramani, P.A. and Michael R.D. (2016). Immunostimulatory effect of the aqueous leaf extract of Phyllanthus niruri on the specific and nonspecific immune responses of Oreochromis mossambicus Peters. Iranian Journal of Veterinary Research. 17: 200.
  50. Nahak, G. and Sahu, R. (2014). Immunostimulatory effects of Ocimum sanctum Linn. leaf extracts in Clarias batrachus Linn. Asian J. Pharm. Clin. Res. 7: 157-163.
  51. Nya, EJ. and Austin, B. (2009a). Use of garlic, Allium sativum, to control Aeromonas hydrophila infection in rainbow trout, Oncorhynchus mykiss (Walbaum). Journal of Fish Diseases. 32: 963-970.
  52. Nya, E.J. and Austin, B. (2009b). Use of dietary ginger, Zingiber officinale Roscoe, as an immunostimulant to control Aeromonas hydrophila infections in rainbow trout, Oncorhynchus mykiss (Walbaum). Journal of Fish Diseases. 32: 971-977.
  53. Payung, C.N., Tumbol, R.A. and Manoppo, H. (2017). Dietary ginger (Zingiber officinale) enhance resistance of Nile tilapia (Oreochromis niloticus) against Aeromonas hydrophila. Aquaculture, Aquarium, Conservation and Legislation. 10: 962-968.
  54. Pransin, M. (2006). Using turmeric (Curcuma longa) in goldfish (Carassius auratus) feed. Master of Science (Aquaculture), Major Aquaculture, Department of Aquaculture, Kasetsart University 86.
  55. Preeti, M. and Seema, G. (2014). Haematological evaluation of Eclipta alba root extract in catfish Clariash batrachus. Journal of Pharmaceutical and Scientific Innovation. 3: 240-244.
  56. Punitha, S.M.J., Babu, M.M., Sivaram, V., et al. (2008). Immunostimulating influence of herbal biomedicines on nonspecific immunity in Grouper Epinephelus tauvina juvenile against Vibrio harveyi infection. Aquaculture International. 16: 511-523.
  57. Radhakrishnan, S., Bhavan, P.S., Seenivasan, C., et al. (2014). Influence of medicinal herbs (Alteranthera sessilis, Eclipta alba and Cissus quadrangularis) on growth and biochemical parameters of the freshwater prawn Macrobrachium rosenbergii. Aquaculture International. 22: 551-572.
  58. Radhakrishnan, S., Saravana Bhavan, P., Seenivasan, C., et al. (2015). Effects of native medicinal herbs (Alternanthera sessilis, Eclipta alba and Cissus quadrangularis) on growth performance, digestive enzymes and biochemical constituents of the monsoon river prawn Macrobrachium malcolmsonii. Aquaculture Nutrition. 21: 496-506.
  59. Rajeswari, P.R., Velmurugan, S., Babu, M.M., et al. (2012a). A study on the influence of selected Indian herbal active principles on enhancing the immune system in Fenneropenaeus indicus against Vibrio harveyi infection. Aquaculture International. 20: 1009-1020.
  60. Rajeswari, R., Umadevi, M., Rahale, C.S., et al. (2012b). Aloe vera: the miracle plant its medicinal and traditional uses in India. Journal of Pharmacognosy and Phytochemistry. 1: 118-124.
  61. Reverter, M., Tapissier-Bontemps, N., Sasal, P. and Saulnier, D. (2017). Use of medicinal plants in aquaculture. Diagnosis and Control of Diseases of Fish and Shellfish. 9: 223-261.
  62. Rosny, H.S., Hossain, M.M.M., Hasan-Uj-Jaman, M., et al. (2016). Dietary supplementation of garlic (Allium sativum) to prevent Acanthocephala infection in aquaculture. International Journal of Fisheries and Aquatic Studies. 4: 188-192.
  63. Sahu, S., Das, B.K., Mishra, B.K., et al. (2007). Effect of Allium sativum on the immunity and survival of Labeo rohita infected with Aeromonas hydrophila. Journal of Applied Ichthyology. 23: 80-86.
  64. Shakya, S.R. (2015). Medicinal uses of ginger (Zingiber officinale Roscoe) improves growth and enhances immunity in aquaculture. International Journal of chemical studies. 3: 83-87.
  65. Shakya, S.R. and Labh, S.N. (2014). Medicinal uses of garlic (Allium sativum) improves fish health and acts as an immunostimulant in aquaculture. European Journal of Biotechnology and Bioscience. 2: 44–47.
  66. Shaluei, F., Nematollahi, A., Naderi Farsani, H.R., Rahimi, R. and Kaboutari Katadj, J. (2017). Effect of ethanolic extract of Zingiber officinale on growth performance and mucosal immune responses in rainbow trout (Oncorhynchus mykiss). Aquaculture Nutrition. 23(4): 814-821. 
  67. Shankar, K and Kiran, BR. (2013). Review on usage of medicinal plants in fish diseases. International Journal of Pharma. and Bio Sciences. 4(3): 975-986.
  68. Sivaram, V., Babu, M.M., Immanuel, G., et al. (2004). Growth and immune response of juvenile greasy groupers (Epinephelus tauvina) fed with herbal antibacterial active principle supplemented diets against Vibrio harveyi infections. Aquaculture. 237: 9-20. https://doi.org/10.1016/j.aquaculture.2004.03.014
  69. Sunitha, C., Mettilda, S. and Vinoliya, J. (2017). Effect of dietary intake of Phyllanthus niruri L. on fingerlings of freshwater fish, Cyprinus carpio L. Int. J. Fisheries Aquatic Studie. 5: 352-9.
  70. Talpur, A.D., Ikhwanuddin, M., Bolong, A-MA. (2013). Nutritional effects of ginger (Zingiber officinale Roscoe) on immune response of Asian sea bass, Lates calcarifer (Bloch) and disease resistance against Vibrio harveyi. Aquaculture. 400: 46-52.
  71. Trejo-Flores, J.V., Luna-González, A., Álvarez-Ruíz, P., et al. (2016). Protective effect of Aloe vera in Litopenaeus vannamei challenged with Vibrio parahaemolyticus and white spot syndrome virus. Aquaculture. 465: 60-64
  72. Vaishnava, M.M., Tripathi, A.K. and Gupta, K.R. (1993). Constituents of Cassia fistula roots. Fitoterapia. 64(1): 93.
  73. Vaseeharan, B., Prasad, G.S., Ramasamy, P. and Brennan, G. (2011). Antibacterial activity of Allium sativum against multidrug-resistant Vibrio harveyi isolated from black gill-diseased Fenneropenaeus indicus. Aquaculture International. 19(3): 531-539. 
  74. Venkatramalingam, K., Christopher, J.G. and Citarasu, T. (2007). Zingiber officinalis an herbal appetizer in the tiger shrimp Penaeus monodon (Fabricius) larviculture. Aquaculture Nutrition.13: 439-443.
  75. Wal, A., Wal, P., Gupta, N., et al. (2013). Medicinal value of Euphorbia tirucalli. Int J Pharm Biol Arch. 4(1): 31-40.
  76. White B. (2007). Ginger: An overview. American family physician. 75: 1689-1691.
  77. Yogeeswaran, A., Velmurugan, S., Punitha, S.M.J., et al. (2012). Protection of Penaeus monodon against white spot syndrome virus by inactivated vaccine with herbal immunostimulants. Fish and Shellfish Immunology. 32: 1058-1067.
  78. Yonar, M.E., Yonar, S.M., İspir, Ü. and Ural, M.Ş. (2019). Effects of curcumin on haematological values, immunity, antioxidant status and resistance of rainbow trout (Oncorhynchus mykiss) against Aeromonas salmonicida subsp. achromogenes. Fish and Shellfish Immunology. 89: 83-90. 
  79. Yusuf, M.S., Hassan, M.A., Tag, H.M., et al. (2017) Influence of turmeric (Curcuma longa) on performance, histomorphology and microbiota of intestine in juvenile tilapia (Oreochromis niloticus). Int. J. Agric. Sci. Vet. Med. 5: 7-16.
  80. Zanuzzo, F.S., Biller-Takahashi, J.D. and Urbinati, E.C. (2012). Effect of Aloe vera extract on the improvement of the respiratory activity of leukocytes of matrinxa during the transport stress. Revista Brasileira de Zootecnia. 41(10): 2299-2302. 

Editorial Board

View all (0)