Agricultural Reviews

  • Chief EditorPradeep K. Sharma

  • Print ISSN 0253-1496

  • Online ISSN 0976-0741

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Agricultural Reviews, volume 38 issue 2 (june 2017) : 129-136

Transgenesis in farm animals-A review

Parul Mehta*, Ankur Sharma, Ramakant Kaushik
1<p>Embryo Biotechnology Lab, Animal Biotechnology Centre, ICAR-National Dairy Research Institute, Karnal-132 001, Haryana, India.</p>
Cite article:- Mehta* Parul, Sharma Ankur, Kaushik Ramakant (2017). Transgenesis in farm animals-A review . Agricultural Reviews. 38(2): 129-136. doi: 10.18805/ag.v38i02.7944.

For a number of decades, attempts have been made to successfully produce transgenic animals which have numerous applications in the biotechnology industry with the foremost emphasis on production of monoclonal antibodies and recombinant proteins of human welfare. Different techniques are adopted in order to produce transgenic farm animals which could be further used as bioreactors. The most common traditional transgenesis technique employed is Somatic Cell Nuclear Transfer (SCNT) using genetically modified somatic cells or stem cells as nuclear donors. This review article summarizes the merits and demerits of the techniques currently used to produce transgenic livestock with major emphasis on somatic cell nuclear transfer. In the end, a brief discussion is done about the novel methods adopted to produce transgenic animals like Zinc Finger Nucleases (ZFN), Transcription Activator-like Effector Nuclease (TALEN) and Clustered regularly interspaced short palindromic repeats (CRISPR). It is expected that the new techniques developed would overcome the problems faced with existing traditional transgenesis methods. 

  1. Abate T., (2012). Four Seasons of Learning and Engaging Small Framers: Progress of Phase 1. PO Box 39063, Nairobi, Kenya: International Crops Research Institute for the Semi-Arid-Tropics. 258 pp.

  2. Anonymous (2014a). Pocket book of agricultural statistics, 2014. GOI, Directorate of Economics & Statistics, New Delhi.

  3. Anonymous (2014b). AICRP Report of All India Coordinated Research Project on MULLaRP. Indian Institute of Pulses Research, Kanpur, India.

  4. Basu P.S., Srivastava M., Singh P., Porwel, P, Kant, R. and Singh J.(2014). High precision phenotyping under controlled versus natural environments. In: Phenomics in Crop Plants: Trends Options and Limitations (eds., J. Kumar, S. Kumar and A. Pratap). Springer India.

  5. Chand R. (2008). The global food crisis: causes, severity and outlook. Economic and Political Weekly 43 (26): 137–144.

  6. Datta, S.K. and Singh B.B. (2015). Production and productivity of pulses: Indian perspectives. Pulses handbook 2015. Pp 34-35.

  7. Dutta S., Kumawat G., Singh B.P., Gupta D.K., Singh S., Dogra V. (2011). Development of genic-SSR markers by deep transcriptome sequencing in pigeonpea (Cajanus cajan (L.). BMC Plant Biol 11:17.

  8. Ganguly M., Molla K.A., Karmakar S., Datta K., Datta S.K. (2014). Development of pod borer-resistant transgenic chickpea using a pod-specific and a constitutive promoter-driven fused cry1 Ab/Ac gene. Theor. Appl. Genet.127(12): 2555-65. 

  9. IIPR. (2011). Vision (2030). Kanpur: Indian Institute of Pulses Research.

  10. Materne M. and Reddy A.A. (2007). Commercial cultivation and Profitability. Pages 173–186 in The Lentil-An Ancient Crop for Modern Times (Yadav SS, Mc Neil DL and Stevenson PC, eds.). Netherlands: Springer.

  11. Praharaj, C.S. and Singh, Ummed (2015). Pulses for food security of India. Pulses Handbook 2015. Pp 82-84.

  12. Prem, Narayan (2013). India’s shattering pulses economy. Agriculture year book 2013. Pp 12-17.

  13. Purushottam and Singh, Deepak (2015). Pulses production and productivity in India. Pulses handbook 2015. Pp 38-40.

  14. Reddy A. Amarender, M.C.S. Bantilan and Geetha Mohan (2013). Pulses Production Scenario: Policy and Technological Options. Policy Brief, 26: May 2013.

  15. Reddy A.A., (2009). Pulses Production Technology: Status and Way Forward. Economic and Political Weekly. 44(52): 73–80, December 2009.

  16. Singh D.P. and Singh B.B. (2011). Breeding for tolerance to abiotic stress in mungbean. J. Food Leg.,24: 83-90.

  17. Singh N.K., Gupta D.K., Jayaswal P.K., Mahato A.K., Dutta S. (2012). The first draft of the pigeon pea genome sequence. J. Plant Biochemistry Biotechnology DOI 10.1007/s13562-011-0088-8.

  18. Varshney R.K., Close T.J., Singh N.K., Hoisington D.A., Cook D.R. (2009). Orphan legume crops enter the genomics era. Current Opinion Plant Biol,12:1-9.

  19. Varshney R.K. Close T.J., Singh N.K., Hoisington D.A., Cook D.R. (2013). Draft genome sequence of chickpea (Cicer arietinum) provides a resource for trait improvement. Nature Biotechnol doi:10.1038/nbt.2491.


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